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洛匹那韦
CAS号 192725-17-0
中文别名 洛吡那韦;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-二甲基苯氧基)乙酰]氨基]-4-羟基-1,6-二苯基-己-2-基]-3-甲基-2-(2-氧代-1,3-二氮杂环己-1-基)丁酰胺
英文别名 (2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
分子量 628.80
分子式 C37H48N4O5
EINECS编号
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物理化学性质

密度: 1.163g/cm3 
沸点: 924.1°C at 760 mmHg 
闪点: 512.7°C 
蒸汽压: 0mmHg at 25°C 
白色至黄褐色粉末,可以任何比例溶于甲醇和乙醇,可溶于异丙醇,不溶于水

产品用途

是一种HIV蛋白酶抑制剂

应用领域

抗爱滋新药,该药品将用于与其他抗逆转录病毒药物联合用药,治疗HIV感染

上下游产品信息




化学品安全说明书(MSDS)



储运特性





安全术语
风险术语
上游原料
L-2-Amino-3-methylbutyric acid; L-2-Aminoisovaleric acid; 2-Aminoisovaleric acid; L-2-Amino-3-methylbutyric acid; L-alpha-Aminoisovaleric acid; L-valine; (S)-(+)-Valine; (S)-alpha-Aminoisovaleric acid(S)-2-((2-cyanoethyl)amino)-3-methylbutanoic acid(S)-2-((2-cyanoethyl)(methoxycarbonyl)amino)-3-methylbutanoic acid(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butyric acid(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanoyl chloride(S)-(-)-Phenylalanine; L-PhenylalanineEthyl 2-bromoacetate; Ethyl bromoacetatebenzyl(chloro)magnesium1-(Chloromethyl)benzene; Benzyl chlorideacetonitrilebenzyl (2S)-2-(dibenzylamino)-3-phenylpropanoate(2S,4E)-5-amino-2-(dibenzylamino)-1,6-diphenyl-4-hexen-3-one(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenyl-3-hexanol(4S)-4-(dibenzylamino)-3-oxo-5-phenylpentanenitrile(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butyric acid2-(2,6-dimethylphenoxy)acetic acid4-[(5-formyl-1H-imidazol-1-yl)methyl]benzonitriletert-butyl (1S,3S,4S)-1-benzyl-4-(dibenzylamino)-3-hydroxy-5-phenylpentylcarbamatetert-butyl (1S,3S,4S)-4-amino-1-benzyl-3-hydroxy-5-phenylpentylcarbamateethyl 2-(2,6-dimethylphenoxy)acetatetert-butyl (1S,3S,4S)-1-benzyl-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenylpentylcarbamateN-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]-2-(2,6-dimethylphenoxy)acetamidemethyl (2S)-2-amino-3-methylbutanoate(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butyric acidbenzyl 3-hydroxypropylcarbamatebenzyl 3-oxopropylcarbamatemethyl (2S)-2-[(3-[[(benzyloxy)carbonyl]amino]propyl)amino]-3-methylbutanoatemethyl (2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanoate(S)-(-)-Phenylalanine; L-Phenylalaninebenzyl(chloro)magnesium(2S)-5-oxo-2-pyrrolidinecarboxylic acidacetonitrilebenzyl (2S)-2-(dibenzylamino)-3-phenylpropanoate(2S,4E)-5-amino-2-(dibenzylamino)-1,6-diphenyl-4-hexen-3-one(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenyl-3-hexanol(4S)-4-(dibenzylamino)-3-oxo-5-phenylpentanenitrile(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butyric acid(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanoyl chloride(2S)-N-[(1S,3S,4S)-1-benzyl-4-(dibenzylamino)-3-hydroxy-5-phenylpentyl]-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanamide(2S)-N-[(1S,3S,4S)-4-amino-1-benzyl-3-hydroxy-5-phenylpentyl]-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanamide(2S,3S,5S)-3-hydroxy-5-([(2S)-3-methyl-2-[2-oxotetrahydro-1(2H)-pyrimidinyl]butanoyl]amino)-1,6-diphenyl-2-hexanaminium (2S)-5-oxo-2-pyrrolidinecarboxylate2-(2,6-dimethylphenoxy)acetyl chloride2-(2,6-dimethylphenoxy)acetic acid