上游原料
3,6-dichloro-4-fluoropyridazine6-chloro-4-methylpyridazin-3-amine6-chloro-5-methylpyridazin-3-amine1-bromo-2,2-dimethoxypropane6-chloro-2,8-dimethylimidazo[1,2-b]pyridazine2,8-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one4,7-diazaspiro[2.5]octane dihydrochloride5-fluoro-2-pyridinamine; 5-fluoro-2-pyridinylaminedimethyl malonate；Methyl malonate;Propanedioic acid dimethyl ester7-fluoro-2-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one1-Amino-1-cyclopropanecarboxylic acid; 1-Aminocyclopropane-1-carboxylic acid; 1-aminocyclopropane carboxylic acid; Carboxycyclopropylamineethyl 1-aminocyclopropane-1-carboxylate hydrochloride2-Chloroacetyl chloride; Chloroacetic chlorideethyl 1-(2-chloroacetamido)cyclopropane-1-carboxylateBenzylamine; Phenylmethanamine7-benzyl-4,7-diazaspiro[2.5]octane-5,8-dione7-benzyl-4,7-diazaspiro[2.5]octanetert-butyl 7-benzyl-4,7-diazaspiro[2.5]octane-4-carboxylatetert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate5-bromo-2-chloropyridine5-bromo-2-nitropyridine；2-Nitro-5-bromopyridine;3-Bromo-6-nitropyridinetert-butyl 7-(6-chloropyridin-3-yl)-4,7-diazaspiro[2.5]octane-4-carboxylatetert-butyl 7-(6-nitropyridin-3-yl)-4,7-diazaspiro[2.5]octane-4-carboxylatetert-butyl 7-(6-aminopyridin-3-yl)-4,7-diazaspiro[2.5]octane-4-carboxylatedi(tert-butyl) malonate; Di-tert-butyl malonatetert-butyl 7-(2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylatetert-butyl 7-(4-oxo-2-tosyl-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylatetert-butyl 7-(2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-4,7-diazaspiro[2.5]octane-4-carboxylate2,8-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine6-chloro-3-pyridazinamine; 6-chloro-3-pyridazinylamine4-bromo-6-chloropyridazin-3-amineMethylmagnesium chloridemethyllithium6-chloro-4-methylpyridazin-3-amineisopropyl acetate6-chloro-2,8-dimethylimidazo[1,2-b]pyridazine2,8-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine
