上游原料
2,6-dichloro-5-fluoronicotinic acid2,6-dichloro-5-fluoronicotinoyl chloride2,6-dichloro-5-fluoronicotinamideOxalyl chloride; 2-Chloro-2-oxoacetyl chloride2-isopropyl-4-methylpyridin-3-amine2,6-dichloro-5-fluoro-N-((2-isopropyl-4-methylpyridin-3-yl)carbamoyl)nicotinamide7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione4,7-dichloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-onetert-butyl (S)-3-methylpiperazine-1-carboxylatetert-butyl (S)-4-(7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)-2-oxo-1,2-dihydropyrido[2,3-d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylatepotassium trifluoro(2-fluoro-6-hydroxyphenyl)boratetert-butyl (3S)-4-(6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)-2-oxo-1,2-dihydropyrido[2,3-d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)-4-((S)-2-methylpiperazin-1-yl)pyrido[2,3-d]pyrimidin-2(1H)-oneAcryloyl chloride; Acrylyl chloride;2-Propenoyl chloride4-methyl-3-oxopentanenitrile2-Propanone; Acetone; beta-ketopropane; chevron acetone;propan-2-one； Dimethyl formaldehyde; Dimethyl ketone; dimethylketal; Ketone propane; Methyl ketone; Propanone; Pyroacetic acid; Pyroacetic ether4-methyl-3-oxo-2-(propan-2-ylidene)pentanenitrile(2Z,4E)-5-(dimethylamino)-2-isobutyryl-3-methylpenta-2,4-dienenitrile2-isopropyl-4-methylnicotinonitrile2-isopropyl-4-methylnicotinamide2-chloro-4-methylnicotinonitrileisopropylmagnesium chloride2-bromo-4-methylpyridin-3-amineisopropylzinc(II) bromide2-isopropyl-4-methylpyridin-3-amine7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione4,7-dichloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-onetert-butyl (S)-3-methylpiperazine-1-carboxylatetert-butyl (3S)-4-(7-chloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylatetert-butyl (3S)-4-(6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)-2-oxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)-4-((S)-2-methylpiperazin-1-yl)-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one1-fluoro-3-methoxybenzene；3-Fluoroanisole;m-Fluoroanisole(2-fluoro-6-methoxyphenyl)boronic acid(2-fluoro-6-hydroxyphenyl)boronic acidpotassium trifluoro(2-fluoro-6-hydroxyphenyl)borate
