上游原料
2-bromo-5-fluorophenol2-bromo-5-fluorophenyl tert-butyl carbonatetert-butyl 3-bromo-6-fluoro-2-hydroxybenzoatetert-butyl 3-bromo-2-((tert-butoxycarbonyl)oxy)-6-fluorobenzoate8-bromo-5-fluoro-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-oneacrylic acid(E)-3-(5-fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)acrylic acid2,3-dibromo-3-(5-fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)propanoic acid(Z)-8-(2-bromovinyl)-5-fluoro-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one(Z)-5-fluoro-2,2-dimethyl-8-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)-4H-benzo[d][1,3]dioxin-4-one(Z)-(2-(5-fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)vinyl)boronic acid(4R,5R)-6-(dimethylamino)-4,5-dihydroxy-2-methyl-4,5-dihydro-1l3,2-oxazin-3(2H)-one(4R,5S)-N-(((dimethylamino)methylene)-l3-oxidanyl)-2-((Z)-2-(5-fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)vinyl)-N,5-dimethyl-1,3,2-dioxaborolane-4-carboxamidediiodomethane(4R,5S)-N-(((dimethylamino)methylene)-l3-oxidanyl)-2-(2-(5-fluoro-2,2-dimethyl-4-oxo-4H-benzo[d][1,3]dioxin-8-yl)cyclopropyl)-N,5-dimethyl-1,3,2-dioxaborolane-4-carboxamide5-fluoro-2,2-dimethyl-8-((1S,2R)-2-((3aS,4S,6S,7aR)-3a,4,5,5,6-pentamethylhexahydrobenzo[d][1,3,2]dioxaborol-2-yl)cyclopropyl)-4H-benzo[d][1,3]dioxin-4-one5-fluoro-2,2-dimethyl-8-((Z)-2-((3aS,4S,6S,7aR)-3a,4,5,5,6-pentamethylhexahydrobenzo[d][1,3,2]dioxaborol-2-yl)vinyl)-4H-benzo[d][1,3]dioxin-4-one5-fluoro-2,2-dimethyl-8-(2-((3aS,4S,6S,7aR)-3a,4,5,5,6-pentamethylhexahydrobenzo[d][1,3,2]dioxaborol-2-yl)cyclopropyl)-4H-benzo[d][1,3]dioxin-4-one2,6-Difluorobenzoic acid2-fluoro-6-hydroxybenzoic acidethyl 2-fluoro-6-hydroxybenzoatemethyl 2-chloroacetate; methyl chloroacetate2-(2-(ethoxycarbonyl)-3-fluorophenoxy)acetic acidethyl 6-fluoro-3-oxo-2,3-dihydrobenzofuran-7-carboxylateethyl 6-fluorobenzofuran-7-carboxylateethyl 7-fluoro-2-hydroxy-2H-benzo[e][1,2]oxaborinine-8-carboxylateethyl (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrobenzo[e]cyclopropa[c][1,2]oxaborinine-4-carboxylateethyl 5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrobenzo[e]cyclopropa[c][1,2]oxaborinine-4-carboxylate2-Bromo-1-ethoxyethyl ethyl ether; 2-Bromo-1,1-diethoxyethane; Bromoacetaldehyde diethylacetalethyl 2-(2,2-diethoxyethoxy)-6-fluorobenzoateethyl (2R,4'S,5'S)-7-fluoro-3',4'-dimethyl-5'-phenyl-2l4-spiro[benzo[e][1,2]oxaborinine-2,2'-[1,3,2]oxazaborolidine]-8-carboxylateDibromomethaneethyl (1aR,7bS)-5-fluoro-1,1a,7b-trihydro-2l4-spiro[benzo[e]cyclopropa[c][1,2]oxaborinine-2,2'-[1,3,2]oxazaborolidine]-4-carboxylate