上游原料
methyl 4-oxopiperidine-3-carboxylate1-(tert-butyl) 3-methyl 4-oxopiperidine-1,3-dicarboxylate(S)-2-amino-N,N-diethyl-3-methylbutanamide1-(tert-butyl) 3-methyl 4-(((S)-1-(diethylamino)-3-methyl-1-oxobutan-2-yl)amino)piperidine-1,3-dicarboxylate3-buten-2-one; methyl vinyl ketone1-(tert-butyl) 3-methyl (S)-4-oxo-3-(3-oxobutyl)piperidine-1,3-dicarboxylate2-(tert-butyl) 8a-methyl (R)-6-oxo-4,6,7,8-tetrahydroisoquinoline-2,8a(1H,3H)-dicarboxylate2,2,2-trifluoroethyl formate2-(tert-butyl) 8a-methyl (R,Z)-7-(hydroxymethylene)-6-oxo-4,6,7,8-tetrahydroisoquinoline-2,8a(1H,3H)-dicarboxylate1-(4-fluorophenyl)hydrazine6-(tert-butyl)4a-methyl (R)-1-(4-fluorophenyl)-1,4,7,8-tetrahydro-6H-pyrazolo[3,4-g]isoquinoline-4a,6(5H)-dicarboxylate2-bromo-4-(trifluoromethyl)pyridinetert-butyl (R)-1-(4-fluorophenyl)-4a-(4-(trifluoromethyl)picolinoyl)-1,4,4a,5,7,8-hexahydro-6H-pyrazolo[3,4-g]isoquinoline-6-carboxylate[1-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-pyrazolo[3,4-g]isoquinolin-4a-yl]-[4-(trifluoromethyl)pyridin-2-yl]methanone1-methyl-1H-pyrazole-4-sulfonyl chloride1-methyl-1H-pyrazole; N-MethylpyrazoleChlorosulfonic acid