上游原料
(2S)-3-Butyn-2-ol; (S)-(-)-3-Butyn-2-ol(2S)-4-(trimethylsilyl)-3-butyn-2-ol(4S)-4-hydroxy-2-pentynoic acid(4S)-4-(acetyloxy)-2-pentynoic acid(Z,4S)-4-(acetyloxy)-2-pentenoic acidtriethyl({(E)-1-[(Z)ethylidene]-2-butenyl}oxy)silane; (E)-1-[(Z)ethylidene]-2-butenyl triethylsilyl ether5-(trimethylsilyl)-4-pentynal(2S,3R,6R)-3,6-dimethyl-2-[4-(trimethylsilyl)-3-butynyl]-3,6-dihydro-2H-pyran-4-yl triethylsilyl ether; (4-{(2S,3R,6R)-3,6-dimethyl-4-[(triethylsilyl)oxy]-3,6-dihydro-2H-pyran-2-yl}-1-butynyl)(trimethyl)silane(2R,3R,5R,6S)-3-hydroxy-2,5-dimethyl-6-[4-(trimethylsilyl)-3-butynyl]tetrahydro-4H-pyran-4-oneN'-{(2R,3S,5S,6S)-3-hydroxy-2,5-dimethyl-6-[4-(trimethylsilyl)-3-butynyl]tetrahydro-4H-pyran-4-ylidene}-4-methylbenzenesulfonohydrazide(2R,3S,5S,6S)-2,5-dimethyl-6-[4-(trimethylsilyl)-3-butynyl]tetrahydro-2H-pyran-3-ol(2R,3S,5S,6S)-6-(3-butynyl)-2,5-dimethyltetrahydro-2H-pyran-3-ol(2R,3S,5S,6S)-6-(2-butynyl)-2,5-dimethyltetrahydro-2H-pyran-3-ol(2R,3S,5S,6S)-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-ol(2R,3S,5S,6S)-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-yl chloromethanesulfonate(2R,3R,5S,6S)-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-yl azide; (2R,3R,5S,6S)-3-azido-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran2-{[tert-butyl(dimethyl)silyl]oxy}acetaldehyde；tert-butyldimethylsilyloxy acetaldehyde(2R,3R,5S,6S)-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-yl azide; (2R,3R,5S,6S)-3-azido-6-[(E)-3-iodo-2-butenyl]-2,5-dimethyltetrahydro-2H-pyrantriethyl{[(E)-1-methylene-2-penten-4-ynyl]oxy}silane; (E)-1-methylene-2-penten-4-ynyl triethylsilyl ethertert-butyl(dimethyl)silyl {(2R,6S)-6-ethynyl-4-[(triethylsilyl)oxy]-3,6-dihydro-2H-pyran-2-yl}methyl ether; tert-butyl({(2R,6S)-6-ethynyl-4-[(triethylsilyl)oxy]-3,6-dihydro-2H-pyran-2-yl}methoxy)dimethylsilane(2R,6R)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-ethynyl-3-hydroxytetrahydro-4H-pyran-4-one(2R,3R,6R)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-ethynyl-3-hydroxytetrahydro-4H-pyran-4-one(2R,3R,6R)-6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-ethynyl-3-[(triisopropylsilyl)oxy]tetrahydro-4H-pyran-4-onetert-butyl(dimethyl)silyl {(2R,5S,6R)-6-ethynyl-4-methylene-5-[(triisopropylsilyl)oxy]tetrahydro-2H-pyran-2-yl}methyl ether; tert-butyl({(2R,5S,6R)-6-ethynyl-4-methylene-5-[(triisopropylsilyl)oxy]tetrahydro-2H-pyran-2-yl}methoxy)dimethylsilane(2R,3S,6R)-2-ethynyl-6-(iodomethyl)-4-methylenetetrahydro-2H-pyran-3-yl triisopropylsilyl ether; {[(2R,3S,6R)-2-ethynyl-6-(iodomethyl)-4-methylenetetrahydro-2H-pyran-3-yl]oxy}(triisopropyl)silane(2R,3S,6R)-2-ethynyl-6-(iodomethyl)-4-methylenetetrahydro-2H-pyran-3-ol(3R,4R,5R,7R)-5-ethynyl-7-(iodomethyl)-1,6-dioxaspiro[2.5]octan-4-ol(3R,4R,5R,7R)-5-ethynyl-7-(iodomethyl)-1,6-dioxaspiro[2.5]oct-4-yl triethylsilyl ether; triethyl{[(3R,4R,5R,7R)-5-ethynyl-7-(iodomethyl)-1,6-dioxaspiro[2.5]oct-4-yl]oxy}silane(3R,4R,5R,7R)-5-{(1E,3E)-5-[(2S,3S,5R,6R)-5-azido-3,6-dimethyltetrahydro-2H-pyran-2-yl]-3-methyl-1,3-pentadienyl}-7-(iodomethyl)-1,6-dioxaspiro[2.5]oct-4-yl triethylsilyl ether; {[(3R,4R,5R,7R)-5-{(1E,3E)-5-[(2S,3S,5R,6R)-5-azido-3,6-dimethyltetrahydro-2H-pyran-2-yl]-3-methyl-1,3-pentadienyl}-7-(iodomethyl)-1,6-dioxaspiro[2.5]oct-4-yl]oxy}(triethyl)silane(2R,3R,5S,6S)-6-((2E,4E)-5-{(3R,4R,5R,7R)-7-(iodomethyl)-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-3-methyl-2,4-pentadienyl)-2,5-dimethyltetrahydro-2H-pyran-3-amine; (2R,3R,5S,6S)-6-((2E,4E)-5-{(3R,4R,5R,7R)-7-(iodomethyl)-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-3-methyl-2,4-pentadienyl)-2,5-dimethyltetrahydro-2H-pyran-3-ylamine(Z,4S)-4-(acetyloxy)-2-pentenoic acid(2R,3R,5S,6S)-6-((2E,4E)-5-{(3R,4R,5R,7R)-7-(iodomethyl)-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-3-methyl-2,4-pentadienyl)-2,5-dimethyltetrahydro-2H-pyran-3-amine; (2R,3R,5S,6S)-6-((2E,4E)-5-{(3R,4R,5R,7R)-7-(iodomethyl)-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-3-methyl-2,4-pentadienyl)-2,5-dimethyltetrahydro-2H-pyran-3-ylamine(1S,2Z)-4-{[(2R,3R,5S,6S)-6-((2E,4E)-5-{(3R,4R,5R,7R)-7-(iodomethyl)-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-3-methyl-2,4-pentadienyl)-2,5-dimethyltetrahydro-2H-pyran-3-yl]amino}-1-methyl-4-oxo-2-butenyl acetate(1S,2Z)-4-{[(2R,3R,5S,6S)-2,5-dimethyl-6-((2E,4E)-3-methyl-5-{(3R,4R,5R)-7-methylene-4-[(triethylsilyl)oxy]-1,6-dioxaspiro[2.5]oct-5-yl}-2,4-pentadienyl)tetrahydro-2H-pyran-3-yl]amino}-1-methyl-4-oxo-2-butenyl acetate(1S,2Z)-4-[((2R,3R,5S,6S)-6-{(2E,4E)-5-[(3R,4R,5R)-4-hydroxy-7-methylene-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino]-1-methyl-4-oxo-2-butenyl acetateMethyl (triphenylphosphoranylidene)acetate; (methoxycarbonylmethylene)triphenylphosphorane；Methyl 2-(triphenyl-lambda(5)-phosphanylidene)acetateethyl 2-(triphenylphosphoranylidene)propanoatetert-butyl (4S,5R)-4-formyl-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylatetert-butyl (4R,5R)-4-[(E)-3-ethoxy-2-methyl-3-oxo-1-propenyl]-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylatetert-butyl (4R,5R)-4-(3-ethoxy-2-methyl-3-oxopropyl)-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylatetert-butyl (2R,3R)-2,5-dimethyl-6-oxotetrahydro-2H-pyran-3-ylcarbamatetert-butyl (2R,3R,5R)-2,5-dimethyl-6-thioxotetrahydro-2H-pyran-3-ylcarbamatemethyl 2-{(2R,3R)-3-[(tert-butoxycarbonyl)amino]-2,5-dimethyl-3,4-dihydro-2H-pyran-6-yl}acetatemethyl 2-{(2S,3S,5R,6R)-5-[(tert-butoxycarbonyl)amino]-3,6-dimethyltetrahydro-2H-pyran-2-yl}acetatetert-butyl (2R,3R,5S,6S)-2,5-dimethyl-6-(2-oxoethyl)tetrahydro-2H-pyran-3-ylcarbamateethyl 2-(triphenylphosphoranylidene)propanoatetert-butyl (2R,3R,5S,6S)-2,5-dimethyl-6-(2-oxoethyl)tetrahydro-2H-pyran-3-ylcarbamateethyl (E)-4-{(2S,3S,5R,6R)-5-[(tert-butoxycarbonyl)amino]-3,6-dimethyltetrahydro-2H-pyran-2-yl}-2-methyl-2-butenoatetert-butyl (2R,3R,5S,6S)-6-[(E)-4-hydroxy-3-methyl-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-ylcarbamatetert-butyl (2R,3R,5S,6S)-6-[(E)-4-bromo-3-methyl-2-butenyl]-2,5-dimethyltetrahydro-2H-pyran-3-ylcarbamate4-methylbenzenesulfinatetert-butyl (2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-ylcarbamate(2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-amine; (2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-ylamine(2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-amine; (2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-ylamine(2S)-2-{[tert-butyl(diphenyl)silyl]oxy}propanalethyl 2-[bis(2,2,2-trifluoroethoxy)phosphoryl]acetateethyl (Z,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-2-pentenoate(Z,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-2-pentenoic acid(Z,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-N-((2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-yl)-2-pentenamide1-(dimethoxymethyl)-4-methoxybenzene(4R,5S,6R)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol(4aR,8R,8aS)-2-(4-methoxyphenyl)hexahydropyrano[3,2-d][1,3]dioxine-6,8-diol(4aR,8R,8aS)-8-hydroxy-2-(4-methoxyphenyl)tetrahydropyrano[3,2-d][1,3]dioxin-6(4H)-one(4aR,8R,8aR)-8-{[tert-butyl(dimethyl)silyl]oxy}-2-(4-methoxyphenyl)tetrahydropyrano[3,2-d][1,3]dioxin-6(4H)-one{[(4aR,8R,8aR)-2-(4-methoxyphenyl)-6-methylenehexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy}(tert-butyl)dimethylsilane; 4-((4aR,8R,8aR)-8-{[tert-butyl(dimethyl)silyl]oxy}-6-methylenehexahydropyrano[3,2-d][1,3]dioxin-2-yl)phenyl methyl ether4-((4aR,8R,8aR)-8-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methylhexahydropyrano[3,2-d][1,3]dioxin-2-yl)phenyl methyl ether; {[(4aR,8R,8aR)-6-methoxy-2-(4-methoxyphenyl)-6-methylhexahydropyrano[3,2-d][1,3]dioxin-8-yl]oxy}(tert-butyl)dimethylsilane(4aR,6S,8R,8aS)-6-methoxy-2-(4-methoxyphenyl)-6-methylhexahydropyrano[3,2-d][1,3]dioxin-8-ol(4aR,6S,8aR)-6-methoxy-2-(4-methoxyphenyl)-6-methyltetrahydropyrano[3,2-d][1,3]dioxin-8(4H)-one(4aR,6S,8aR)-6-methoxy-2-(4-methoxyphenyl)-6-methyltetrahydropyrano[3,2-d][1,3]dioxin-8(4H)-one(4aR,6S,8aS)-6-methoxy-2-(4-methoxyphenyl)-6-methyl-8-methylenehexahydropyrano[3,2-d][1,3]dioxine; 4-[(4aR,6S,8aS)-6-methoxy-6-methyl-8-methylenehexahydropyrano[3,2-d][1,3]dioxin-2-yl]phenyl methyl ether{(2R,3S,6S)-6-methoxy-3-[(4-methoxybenzyl)oxy]-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl}methanol{(2R,3S,6S)-6-methoxy-3-[(4-methoxybenzyl)oxy]-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl}methyl pivalate[(2R,3S,6S)-3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl]methyl pivalate((2R,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl)methyl pivalate((2R,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl)methanol(2S,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-carbaldehyde(Z,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-N-((2R,3R,5S,6S)-2,5-dimethyl-6-{(E)-3-methyl-4-[(4-methylphenyl)sulfonyl]-2-butenyl}tetrahydro-2H-pyran-3-yl)-2-pentenamide(2S,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-carbaldehyde(1S,3E)-1-((2R,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl)-5-{(2S,3S,5R,6R)-5-[((Z,4S)-4-{[tert-butyl(diphenyl)silyl]oxy}-2-pentenoyl)amino]-3,6-dimethyltetrahydro-2H-pyran-2-yl}-3-methyl-2-[(4-methylphenyl)sulfonyl]-3-pentenyl benzoate(Z,4S)-N-{(2R,3R,5S,6S)-6-[(2E,4E)-5-((2R,3S,6S)-3-{[tert-butyl(dimethyl)silyl]oxy}-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl)-3-methyl-2,4-pentadienyl]-2,5-dimethyltetrahydro-2H-pyran-3-yl}-4-{[tert-butyl(diphenyl)silyl]oxy}-2-pentenam(Z,4S)-4-hydroxy-N-((2R,3R,5S,6S)-6-{(2E,4E)-5-[(2R,3S,6S)-3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)-2-pentenamide(1S,2Z)-4-[((2R,3R,5S,6S)-6-{(2E,4E)-5-[(2R,3S,6S)-3-(acetyloxy)-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino]-1-methyl-4-oxo-2-butenyl acetate(1S,2Z)-4-[((2R,3R,5S,6S)-6-{(2E,4E)-5-[(2R,3S,6S)-3-(acetyloxy)-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino]-1-methyl-4-oxo-2-butenyl acetate(1S,2Z)-4-[((2R,3R,5S,6S)-6-{(2E,4E)-5-[(2R,3S,6S)-3-hydroxy-6-methoxy-6-methyl-4-methylenetetrahydro-2H-pyran-2-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino]-1-methyl-4-oxo-2-butenyl acetate(1S,2Z)-4-[((2R,3R,5S,6S)-6-{(2E,4E)-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadienyl}-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino]-1-methyl-4-oxo-2-butenyl acetate
