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恩曲他滨
CAS号 143491-57-0
中文别名 5-氟-1-(2R,5S)-[2-羟甲基-1,3-氧硫环-5-酰]胞嘧啶;依曲西他滨;恩曲他滨 企标 98.0+%
英文别名 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-(2r-cis)-2(1h)-pyrimidinone; (-)-BETA-2',3'-DIDEOXY-5-FLUORO-3'-THIACYTIDINE; EMTRITABINE; FTC; FUMITREMORGIN C; SM-Q; EMTRICITABIN; EMTRITABINE 98.0+%; 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone,(-)-FTC,(-)-b-23Dideoxy-5-flu; 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)-b-23Dideoxy-5-fluoro-3thiacytidine, 524W91, BW-52491, Coviracil,; Entricitabine; 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl-; 2'-deoxy-5-fluoro-3'-thiacytidine; 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)--2’,3’-Dideoxy-5-fluoro-3’-thiacytidine, 524W91, BW-52491, Coviracil
分子量 247.25
分子式 C8H10FN3O3S
EINECS编号
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物理化学性质

外观性状 白色、类白色粉末或结晶性粉末
熔点 
136-140 ℃ 

产品用途

应用领域







上下游产品信息




化学品安全说明书(MSDS)



储运特性





安全术语
风险术语
上游原料
1,4-dithiane-2,5-diol2-Oxoacetic acid; Glyoxylic Acid(2S,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylic acid(2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylic acid(2R,5R)-5-(acetoxy)-1,3-oxathiolane-2-carboxylic acid(2R,5S)-2-isopropyl-5-methylcyclohexanol(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-(acetyloxy)-1,3-oxathiolane-2-carboxylate 5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine(2S,5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate(2R,5S)-2-isopropyl-5-methylcyclohexanol2-Oxoacetic acid; Glyoxylic Acid(2R,5S)-2-isopropyl-5-methylcyclohexyl 2-oxoacetate1,4-dithiane-2,5-diol(5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate(5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate(2S,5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine(5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate(5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-chloro-1,3-oxathiolane-2-carboxylate(2S,5R)-(1S,2R,5S)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine(5-oxo-1,3-oxathiolan-2-yl)methyl butyrate(5-acetoxy-1,3-oxathiolan-2-yl)methyl butyrate(5-chloro-1,3-oxathiolan-2-yl)methyl butyrate(5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl butyrate(rac)-[(2R,5S)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl butyrate2-Propen-1-ol; Allyl alcoholtert-Butylchlorodiphenylsilane;tert-Butyldiphenylchlorosilane;tert-Butyldiphenylsilyl chloride(allyloxy)(tert-butyl)diphenylsilane2-[[tert-butyl(diphenyl)silyl]oxy]acetaldehyde2-sulfanylacetic acid2-(((tert-butyldiphenylsilyl)oxy)methyl)-1,3-oxathiolan-5-one(2R)-2-({[tert-butyl(diphenyl)silyl]oxy}methyl)-1,3-oxathiolan-4-yl acetate5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine4-amino-1-((2S,5R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one(3S,4S,5S,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrol(2S,3R,4S,5S)-4,5,6-tris(acetoxy)-2-([[(4-methylphenyl)sulfonyl]oxy]methyl)tetrahydro-2H-pyran-3-yl acetate(2R,3S,4S,5S,6S)-3,5-bis(acetoxy)-2-bromo-6-([[(4-methylphenyl)sulfonyl]oxy]methyl)tetrahydro-2H-pyran-4-yl acetate(2S,3S,4S)-8-oxa-6-thiabicyclo[3.2.1]octane-2,3,4-triol[(2R,5R)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,3-oxathiolan-2-yl]methanoltert-butyl([(2R,5R)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,3-oxathiolan-2-yl]methoxy)dimethylsilane; tert-butyl(dimethyl)silyl [(2R,5R)-5-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-1,3-oxathiolan-2-yl]methyl ether(1R)-1-[(2R,5R)-2-([[tert-butyl(dimethyl)silyl]oxy]methyl)-1,3-oxathiolan-5-yl]-1,2-ethanediol(2R)-2-[(acetoxy)methyl]-1,3-oxathiolane-5-carboxylic acid(2R)-2-[(acetoxy)methyl]-1,3-oxathiolan-5-yl acetateN-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]acetamide[(2R,5S)-5-[4-(acetamido)-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl acetate2-oxoethyl benzoate4-amino-5-fluoro-2(1H)-pyrimidinone; 5-fluorocytosine1,4-dithiane-2,5-diol5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine[(2R,5S)-5-[4-(acetamido)-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl benzoate4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone[(2R,5S)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl dihydrogen phosphate4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone[5-(acetoxy)-1,3-oxathiolan-2-yl]methyl benzoate(rac)-({(2R*,5S*)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl}methyl dihydrogen phosphate)4-amino-5-fluoro-2(1H)-pyrimidinone; 5-fluorocytosine2-sulfanylacetic acid5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine4-amino-5-fluoro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone(Z)-2-butene-1,4-diol(Z)-4-(butyryloxy)-2-butenyl butyrate2-oxoethyl butyrate(5-oxo-1,3-oxathiolan-2-yl)methyl butyrate[5-(acetoxy)-1,3-oxathiolan-2-yl]methyl butyrate(rac)-[(2R,5S)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl butyrate[(2S,5R)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl butyrate(-)-cis-[(2R,5S)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl butyrate4-amino-5-fluoro-2(1H)-pyrimidinone; 5-fluorocytosine2-sulfanylacetic acid5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine(Z)-2-butene-1,4-diol(Z)-4-(butyryloxy)-2-butenyl butyrate(5-oxo-1,3-oxathiolan-2-yl)methyl butyrate(rac)-[(2R,5S)-5-[4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl]-1,3-oxathiolan-2-yl]methyl butyratebenzyl 6-oxo-5,6,7,8-tetrahydro-2-naphthalenylcarbamate2-hydroxy-2-methoxyethyl butyrate[(2R)-5-oxo-1,3-oxathiolan-2-yl]methyl butyrate[(2R)-5-(acetoxy)-1,3-oxathiolan-2-yl]methyl butyrate[(2R)-5-chloro-1,3-oxathiolan-2-yl]methyl butyrate